BDBM375944 US10947243, Example 10::US9914735, Example 10

SMILES C[C@@H](Oc1nc(cc2nn(C)cc12)-c1cnn(c1)C1CCC(F)(F)CC1)[C@H]1CNC(=O)C1

InChI Key InChIKey=NALGZACUGTTXDW-ZIAGYGMSSA-N

Data  14 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 375944   

TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM375944(US10947243, Example 10 | US9914735, Example 10)
Affinity DataIC50: >1.00E+4nMAssay Description:FLT3 is obtained from Invitrogen in 50 mM Tris (pH7.5); 100 mM NaCl; 0.05 mM EDTA, 0.05% NP-40, 2 mM DTT; 50% Glycerol # PV3182; Lot 286671; sequence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM375944(US10947243, Example 10 | US9914735, Example 10)
Affinity DataIC50: >1.00E+4nMAssay Description:Human GSK3beta (expressed and prified from SF21 cells) is obtained from the University Dundee/Scotland (Dr. James Hastie—Dept. of Biochemistry) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent